I'm not going to try and explain it because there is not one simple solution. Using a pair of turbos, regardless of the configuration requires extremely careful design.
Using a mechanical supercharger together with a turbo(super)charger is even more radical. VW has managed this to great effect in the 1.4 TFSi engine but I suspect that the development costs were pretty high and that the oeprating principles are pretty complex. It's not the first of its kind but it's probably the first to hit truly mass market cars.
There is no simple one-size-fits-all configuration.
I steer away from
mods to be honest, apart from a decent custom ECU remap I have never modified any cars. Which is not to say that it shouldn't be done, but I can think of easier and cheaper ways to ramp up usable performance, such as buying a different car in the first place.